POEMS syndrome

Clinical characteristics of POEMS syndrome with plasma cell myeloma

浆细胞性乳腺炎X线表现伴骨髓瘤的POEMS综合征的临床特点

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Objective: To analysis the cause of misdiagnosis of POEMS syndrome and to reduce the misdiagnosis or mistreatment.

目的：探讨POEMS综合征的误诊原因，以减少临床误诊误治。方法：2003~2005年该科收治2例POEMS综合征，并结合收集的88例POEMS综合征患者临床资料进行分析。

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Objective: To explore the clinical characteristics of POEMS syndrome with plasma cell myeloma.

目的：探讨伴骨髓瘤的POEMS综合征的临床特点。

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POEMS syndrome and hereditary neurofibromatosis type I ( NF I) are two different diseases with different causes and pathogenesis but both can cause multiple system lesions. The coexisting case was rare.

POEMS综合征和遗传性神经纤维瘤病I型（NFⅠ）是不同病因不同发病机制致病的两种疾病，但均可引起多系统损害，症状体征有交叉，二者合并病例很罕见。

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Conclusions POEMS syndrome is a rare multisystem disorder of obscure pathogenesis with some symptom complexes including polyneuropathy, organomegaly, endocrinopathy, M-proteins and skin changes.

结论POEMS综合征是一少见的多系统损害疾病，发病机制不很清楚，常有多发性神经病、脏器肿大、内分泌病、M-蛋白和皮肤改变症状。

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Furthermore, 25% of POEMS syndrome patients have co-existent Castleman disease.

另外，POEMS综合征患者还常常伴发有Castleman病（25%）。

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Endocrinopathy of poems syndrome-analysis of 11 cases

11例POEMS综合征病例内分泌改变报告及文献复习

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